Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study.

doi:10.1016/j.nutres.2023.08.008

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Article

Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study.

Nutrition research (New York, N.Y.) - 1 Nov 2023

Fajardo Cristina Moreno, Cerda Alvaro, Bortolin Raul Hernandes, de Oliveira Raquel, Stefani Tamires Invencioni Moraes, Dos Santos Marina Aparecida, Braga Aécio Assunção, Dorea Egídio Lima, Bernik Márcia Martins Silveira, Bastos Gisele Medeiros, Sampaio Marcelo Ferraz, Damasceno Nágila Raquel Teixeira, Verlengia Rozangela, de Oliveira Maria Rita Marques, Hirata Mario Hiroyuki, Hirata Rosario Dominguez Crespo

Abstract excerpt

Polymorphisms in genes of leptin-melanocortin and insulin pathways have been associated with obesity and type 2 diabetes. We hypothesized that polymorphisms in IRS1, IRS2, MC3R, and MC4R influence metabolic and inflammatory markers and food intake composition in Brazilian subjects. This exploratory pilot study included 358 adult subjects. Clinical, anthropometric, and laboratory data were obtained through...

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PMID: 37716291
DOI: 10.1016/j.nutres.2023.08.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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