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Article

Saliva DNA: An alternative biospecimen for single nucleotide polymorphism chromosomal microarray analysis in autism.

American journal of medical genetics. Part A - 1 Dec 2023

Wright Dale Cameron, Baluyot Maria Lourdes, Carmichael Johanna, Darmanian Artur, Jose Ngaire, Ngo Con, Heaps Luke St, Yendle Amber, Holman Katherine, Ziso Sylvia, Khan Feroza, Masi Anne, Silove Natalie, Eapen Valsa

Abstract excerpt

Chromosomal microarray analysis (CMA) is typically performed for investigation of autism using blood DNA. However, blood collection poses significant challenges for autistic children with repetitive behaviors and sensory and communication issues, often necessitating physical restraint or sedation. Noninvasive saliva collection offers an alternative, however, no published studies to date have evaluated saliva DNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37715344
DOI: 10.1002/ajmg.a.63400

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