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Article

Elucidating the role of dsRNA sensing and Toll6 in antiviral responses of Culex quinquefasciatus cells

30 Aug 2023

Abstract excerpt

The first step of any immune response is the recognition of foreign molecular structures inside the host organism. An important molecule that is generally foreign to eukaryotic cells is long double-stranded RNA (dsRNA), which can be generated during virus replication. The mechanisms of sensing viral dsRNA are well-studied in mammalian systems but are only poorly understood in insects, including disease vectors...

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PMID: 37712057
DOI: 10.3389/fcimb.2023.1251204

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