Article
Genetic markers associated with adverse reactions of radioiodine therapy in thyroid cancer patients.
Drug metabolism and personalized therapy - 1 Sept 2023
Denisenko Natalia P, Kachanova Anastasia A, Sychev Ivan V, Shuev Gregory N, Perfilieva Oksana M, Mukhamadiev Reis H, Kazakov Ruslan E, Milyutina Olga I, Konenkova Olga V, Ryzhkin Sergey A, Zhmaeva Elena M, Kirienko Sergey L, Ivashchenko Dmitriy V, Bure Irina V, Ametov Alexander S, Poddubnaya Irina V, Mirzaev Karin B, Sychev Dmitry A
Abstract excerpt
OBJECTIVES: Radioactive iodine therapy is considered for patients with certain clinicopathological factors that predict a significant risk of recurrence, distant metastases of thyroid cancer or disease-specific mortality. The aim of the study was to investigate the association between polymorphisms of genes, products of which are involved in the processes of DNA damage response and autophagy, and the adverse...
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