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Article

Distinct disease features of acute and persistent genotype 3 hepatitis E virus infection in immunocompetent and immunosuppressed Mongolian gerbils.

PLoS pathogens - 1 Sept 2023

Subramaniam Sakthivel, Fares-Gusmao Rafaelle, Sato Shinya, Cullen John M, Takeda Kazuyo, Farci Patrizia, McGivern David R

Abstract excerpt

Hepatitis E virus (HEV) causes self-limited acute hepatitis in immunocompetent individuals and can establish chronic infection in solid organ transplant recipients taking immunosuppressive drugs. A well characterized small animal model is needed to understand HEV pathogenesis. In this study, we established a robust model to study acute and persistent HEV infection using Mongolian gerbils (Meriones unguiculatus)...

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Identifiers

PMID: 37703304
DOI: 10.1371/journal.ppat.1011664
PMCID: PMC10519604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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