Article
Brain-derived neurotrophic factor (Val66Met) polymorphism and olfactory ability in young adults.
Journal of biomedical science - 7 Aug 2013
Tonacci Alessandro, Borghini Andrea, Mercuri Antonella, Pioggia Giovanni, Andreassi Maria Grazia
Abstract excerpt
BACKGROUND: Brain- derived neurotrophic factor (BDNF) is linked to neurodegenerative diseases (e.g. Alzheimer disease and Parkinson disease) which are often characterized by olfactory impairment. A specific single nucleotide polymorphism of the BDNF gene, the Val66Met, modulates intracellular trafficking and activity-dependent secretion of BDNF protein. The aim of this study was to investigate a possible...
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