Article
Denture use and risk for cardiometabolic disease: observational and Mendelian randomization analyses.
European journal of preventive cardiology - 5 Jan 2024
Liu Yunan, Qin Haiqiang, Li Tongtong, Feng Chengwu, Han Han, Cao Yaying, Su Yang, He Haihao, Yuan Changzheng, Sun Meng, Clarke Robert, Gan Wei, Tonetti Maurizio, Zong Geng
Abstract excerpt
AIMS: Denture use may potentially increase the risk of cardiometabolic diseases (CMDs), but the casual relevance and strength of the associations are currently unknown. METHODS AND RESULTS: A total of 495 938 participants from the UK Biobank were included in the observational analyses. Linkage disequilibrium score (LDSC) regression and Mendelian randomization analyses were employed to estimate genetic correlation...
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