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Evolution of transient RNA structure–RNA polymerase interactions in respiratory RNA virus genomes

1 Jul 2023

Abstract excerpt

Abstract RNA viruses are important human pathogens that cause seasonal epidemics and occasional pandemics. Examples are influenza A viruses (IAV) and coronaviruses (CoV). When emerging IAV and CoV spill over to humans, they adapt to evade immune responses and optimize their replication and spread in human cells. In IAV, adaptation occurs in all viral proteins, including the viral ribonucleoprotein (RNP) complex....

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PMID: 37692892
DOI: 10.1093/ve/vead056

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