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Targeting triple-negative breast cancer cells with a β1-integrin binding aptamer

16 Aug 2023

Abstract excerpt

Targeted therapies have increased the treatment options for triple-negative breast cancer patients. However, the paucity of targetable biomarkers and tumor heterogeneity have limited the ability of precision-guided interventions to live up to their full potential. As affinity-targeting ligands, aptamers show high selectivity toward target molecules. Compared with antibodies, aptamers have lower molecular weight,...

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PMID: 37680989
DOI: 10.1016/j.omtn.2023.08.015

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