Article

Statistical mining of triple-negative breast cancer-specific nanobodies among huge libraries from immunized alpacas

2023-02-23

Abstract excerpt

Breast cancer can be classified into several types according to the expression patterns of human epidermal growth factor receptor 2 (Her2), oestrogen receptor (ER), and progesterone receptor (PgR) proteins. The prognosis of patients with tumors showing low Her2 expression and no ER and PgR expression—categorized as triple-negative breast cancer (TNBC)—is worst among these groups. Due to the lack of specific antibo...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 261f40b8-948e-5ec1-b80e-696aee147c2b
DOI: 10.1101/2023.02.23.529685

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Statistical mining of triple-negative breast cancer-specific nanobodies among huge libraries from immunized alpacasDOI 10.1101/2023.02.23.529685Read

Statistical mining of triple-negative breast cancer-specific nanobodies among huge libraries from immunized alpacasSemantic proximity Read

Nanobodies effectively modulate the enzymatic activity of CD38 and allow specific imaging of CD38+ tumors in mouse models in vivoSemantic proximity Read

TCR-Engineered T Cells Directed against Ropporin-1 Constitute a Safe and Effective Treatment for Triple-Negative Breast CancerSemantic proximity Read

Single-domain antibodies: a versatile and rich source of binders for breast cancer diagnostic approachesSemantic proximity Read

Cancer ImmunomicsSemantic proximity Read

TCR-engineered T-cells directed against Ropporin-1 constitute a safe and effective treatment for triple-negative breast cancer in near-clinical modelsSemantic proximity Read

Nanoscale mapping and organization analysis of target proteins on cancer cells from B-cell lymphoma patientsSemantic proximity Read

De novo identification of tumor-specific internalizing human antibody–receptor pairs by phage-display methodsSemantic proximity Read

Retrospective analysis of the preparation and application of immunotherapy in cancer treatment (Review)Semantic proximity Read

Diagnostic Markers of Ovarian Cancer by High-Throughput Antigen Cloning and Detection on ArraysSemantic proximity Read

Antibody Phage Display Libraries: Contributions to OncologySemantic proximity Read

Targeting triple-negative breast cancer cells with a β1-integrin binding aptamerSemantic proximity Read