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CASP3 gene expression and the role of caspase 3 in the pathogenesis of depressive disorders

6 Sept 2023

Abstract excerpt

BACKGROUND: The aim of our study was to evaluate the expression of the CASP3 gene at both mRNA and protein levels in patients with depressive disorders and to determine the impact of caspase 3 in the pathogenesis of depression; METHODS: A total of 290 subjects, including 190 depressed patients and 100 healthy controls, participated in the study. Socio-demographic and clinical data were collected, and the severity...

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PMID: 37674109
DOI: 10.1186/s12888-023-05153-5

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