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Article

Exploring the Role of Plasma Lipids and Statin Interventions on Multiple Sclerosis Risk and Severity: A Mendelian Randomization Study.

Neurology - 24 Oct 2023

Almramhi Mona M, Finan Chris, Storm Catherine S, Schmidt Amand F, Kia Demis A, Coneys Rachel, Chopade Sandesh, Hingorani Aroon D, Wood Nick W

Abstract excerpt

BACKGROUND AND OBJECTIVES: There has been considerable interest in statins because of their pleiotropic effects beyond their lipid-lowering properties. Many of these pleiotropic effects are predominantly ascribed to Rho small guanosine triphosphatases (Rho GTPases) proteins. We aimed to genetically investigate the role of lipids and statin interventions on multiple sclerosis (MS) risk and severity. METHOD: We...

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Source

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Identifiers

PMID: 37657941
DOI: 10.1212/WNL.0000000000207777
PMCID: PMC10624499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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