Article
Genomic analysis of lineage-specific transmission of multidrug resistance tuberculosis in China.
Emerging microbes & infections - 1 Dec 2024
Li Yi-Fan, Kong Xiang-Long, Song Wan-Mei, Li Ya-Meng, Li Ying-Ying, Fang Wei-Wei, Yang Jie-Yu, Yu Chun-Bao, Li Huai-Chen, Liu Yao
Abstract excerpt
OBJECTIVES: We investigated the genetic diversities and lineage-specific transmission dynamics of multidrug-resistant tuberculosis (MDR-TB), with the goal of determining the potential factors driving the MDR epidemics in China. METHODS: We curated a large nationwide Mycobacterium tuberculosis (M. tuberculosis) whole genome sequence data set, including 1313 MDR strains. We reconstructed the phylogeny and mapped...
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