Article
H2A.Z demarcates intergenic regions of the plasmodium falciparum epigenome that are dynamically marked by H3K9ac and H3K4me3.
PLoS pathogens - 16 Dec 2010
Bártfai Richárd, Hoeijmakers Wieteke A M, Salcedo-Amaya Adriana M, Smits Arne H, Janssen-Megens Eva, Kaan Anita, Treeck Moritz, Gilberger Tim-Wolf, Françoijs Kees-Jan, Stunnenberg Hendrik G
Abstract excerpt
Epigenetic regulatory mechanisms and their enzymes are promising targets for malaria therapeutic intervention; however, the epigenetic component of gene expression in P. falciparum is poorly understood. Dynamic or stable association of epigenetic marks with genomic features provides important clues about their function and helps to understand how histone variants/modifications are used for indexing the Plasmodium...
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