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The chromatin bound proteome of the human malaria parasite

1 Feb 2020

Abstract excerpt

Proteins interacting with DNA are fundamental for mediating processes such as gene expression, DNA replication and maintenance of genome integrity. Accumulating evidence suggests that the chromatin of apicomplexan parasites, such as Plasmodium falciparum , is highly organized, and this structure provides an epigenetic mechanism for transcriptional regulation. To investigate how parasite chromatin structure is...

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PMID: 32017676
DOI: 10.1099/mgen.0.000327

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