Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer

27 Aug 2023

Abstract excerpt

BACKGROUND: In humans, muscle-invasive bladder cancer (MIBC) is highly aggressive and associated with a poor prognosis. With a high mutation load and large number of altered genes, strategies to delineate key driver events are necessary. Dogs and cats develop urothelial carcinoma (UC) with histological and clinical similarities to human MIBC. Cattle that graze on bracken fern also develop UC, associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Veterinary Oncology Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37635261
DOI: 10.1186/s13059-023-03026-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancerPMID 37635261Read ↗

Cross‐species analysis of the canine and human bladder cancer transcriptome and exomeSemantic proximity Read ↗

Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancerSemantic proximity Read ↗

Convergent biology, divergent drivers: a cross-species comparison of human and canine invasive urothelial carcinomaSemantic proximity Read ↗

Homologous Mutation to Human BRAF V600E Is Common in Naturally Occurring Canine Bladder Cancer--Evidence for a Relevant Model System and Urine-Based Diagnostic Test.Semantic proximity Read ↗

Feline Cancers: Cat-aloging the Mutational Landscape.Semantic proximity Read ↗

Cross-species oncogenic signatures of breast cancer in canine mammary tumors.Semantic proximity Read ↗

Whole exome sequencing analysis of canine urothelial carcinomas without BRAF V595E mutation: Short in-frame deletions in BRAF and MAP2K1 suggest alternative mechanisms for MAPK pathway disruptionSemantic proximity Read ↗

Basal and Luminal Molecular Subtypes in Naturally-Occurring Canine Urothelial Carcinoma are Associated with Tumor Immune Signatures and Dog BreedSemantic proximity Read ↗

RNAseq expression patterns of canine invasive urothelial carcinoma reveal two distinct tumor clusters and shared regions of dysregulation with human bladder tumors.Semantic proximity Read ↗

Establishing a Canine Urothelial Organoid Repository: A Platform for Comparative and Translational Carcinoma StudiesSemantic proximity Read ↗

The shared selection landscape of dog and human cancersSemantic proximity Read ↗

Naturally Occurring Canine Invasive Urinary Bladder Cancer: A Complementary Animal Model to Improve the Success Rate in Human Clinical Trials of New Cancer DrugsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.