Article
Population Pharmacokinetic Analysis of Follicle-Stimulating Hormone During Ovarian Stimulation: Relation with Weight, Prolactin and Gene Polymorphism in THADA and ADIPOQ.
Clinical pharmacokinetics - 1 Oct 2023
Zhang Xiaowei, Sui Yu, Yu Lei, Zhou Min, Zhang Chong, Liu Danhua, Chen Xinren, Yang Liqun, Sui Yang
Abstract excerpt
BACKGROUND: Personalisation strategies of ovarian stimulation for in vitro fertilisation (IVF)/ intracytoplasmic sperm injection (ICSI) treatments using exogenous follicle-stimulating hormone (FSH) have been extensively studied over the past 20 years. This research aimed to develop a FSH population pharmacokinetic (PPK) model taking into account the contribution of gene polymorphisms in Chinese reproductive-age...
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