Article
Potential Role of Antibodies against Aquaporin-1 in Patients with Central Nervous System Demyelination.
International journal of molecular sciences - 19 Aug 2023
Pechlivanidou Maria, Xenou Konstantina, Tzanetakos Dimitrios, Koutsos Emmanuel, Stergiou Christos, Andreadou Elisabeth, Voumvourakis Konstantinos, Giannopoulos Sotirios, Kilidireas Constantinos, Tüzün Erdem, Tsivgoulis Georgios, Tzartos Socrates, Tzartos John
Abstract excerpt
Aquaporins (AQPs; AQP0-AQP12) are water channels expressed in many and diverse cell types, participating in various functions of cells, tissues, and systems, including the central nervous system (CNS). AQP dysfunction and autoimmunity to AQPs are implicated in several diseases. The best-known example of autoimmunity against AQPs concerns the antibodies to AQP4 which are involved in the pathogenesis of...
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