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Article

Immune-related biomarker risk score predicts prognosis in prostate cancer.

Aging - 10 Nov 2020

Liu Zezhen, Zhong Jiehui, Cai Chao, Lu Jianming, Wu Wenqi, Zeng Guohua

Abstract excerpt

In this study, we constructed a model using a Cox proportional hazards model based on the expression of eight immune-related genes that were associated with prognosis in prostate cancer: EDNRB, ANGPTL2, TNFSF15, TNFRSF10D, EDN2, BMP2, NLRP14, and PLK1. We then identified associations between risk scores calculated with the model, tumor microenvironment characteristics, and immune cell infiltration. Prostate...

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Biomarkers, Tumor
Gene Regulatory Networks
Genetic Predisposition to Disease
Prognosis
Proportional Hazards Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prostatic Neoplasms

Tumor Microenvironment

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Identifiers

PMID: 33197890
DOI: 10.18632/aging.103921
PMCID: PMC7746334

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