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Article

Temporally complex inflammatory networks in an animal model reveal signatures for interstitial cystitis and bladder pain syndrome phenotype.

Neurourology and urodynamics - 1 Nov 2023

Shah Ashti M, Vodovotz Yoram, Yoshimura Naoki, Chermansky Christopher J, Fitzgerald Jocelyn, Tyagi Pradeep

Abstract excerpt

INTRODUCTION AND OBJECTIVE: Interstitial cystitis and bladder pain syndrome (IC/BPS) presents with symptoms of debilitating bladder pain and is typically a diagnosis of exclusion. The cystoscopic detection of Hunner's lesions increases the likelihood of detecting tissue inflammation on bladder biopsy and increases the odds of therapeutic success with anti-inflammatory drugs. However, the identification of this...

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PMID: 37587846
DOI: 10.1002/nau.25267
PMCID: PMC10615708

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