Article
A Ratiometric SERS Probe for Imaging the Macrophage Phenotypes in Live Mice with Epilepsy and Brain Tumor.
Advanced healthcare materials - 1 Oct 2023
Duan Wenjia, Wang Cong, Jiang Yiqing, Sui An, Li Zhi, Wang Lu, Lei Zuhai, Aime Silvio, Yu Jinhua, Li Cong
Abstract excerpt
Macrophage performs multiple functions such as pathogen phagocytosis, antigen presentation, and tissue remodeling by polarizing toward a spectrum of phenotypes. Dynamic imaging of macrophage phenotypes is critical for evaluating disease progression and the therapeutic response of drug candidates. However, current technologies cannot identify macrophage phenotypes in vivo. Herein, a surface-enhanced Raman...
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