Article
Molecular characterization of patients with chronic hepatitis C virus infection in Jordan: implications on response to direct-acting antiviral therapy.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Oct 2023
Fuentes Ana, Abu-Dayyeh Issa, de Salazar Adolfo, Khasharmeh Rehab, Al-Shabatat Fatima, Jebrin Samer, Chueca Natalia, Hamdan Faris M, Albtoush Yazan, Al-Shaer Omar Abu, Rashid Mohammed M, AlMohsen Oday, Al-Jbour Mohammad, Abdelnour Amid, García Federico
Abstract excerpt
OBJECTIVES: To investigate the molecular characteristics of Hepatitis C Virus (HCV) detected in patients with chronic HCV infection in Jordan. METHODS: The study included 48 Jordanian treatment-naïve patients with active chronic HCV recruited from seven governorates. HCV genotype and the resistance-associated substitutions (RAS) profile were investigated by next-generation sequencing of the NS5B, NS5A, and NS3...
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