Article
Genetic Subtypes and Natural Resistance Mutations in HCV Genotype 4 Infected Saudi Arabian Patients.
Viruses - 14 Sept 2021
Di Stefano Mariantonietta, Ismail Mona H, Leitner Thomas, Faleo Giuseppina, Elmnan Adem Saada A, Elamin Mohamed O M E, Eltreifi Obeidi, Alwazzeh Marwan J, Fiore Jose R, Santantonio Teresa A
Abstract excerpt
This study aimed to characterize the HCV genetic subtypes variability and the presence of natural occurring resistance-associated substitutions (RASs) in Saudi Arabia patients. A total of 17 GT patients were analyzed. Sequence analysis of NS3, NS5A, and NS5B regions was performed by direct sequencing, and phylogenetic analyses were used to determine genetic subtypes, RAS, and polymorphisms. Nine patients were...
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