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Article

Protein regulator of cytokinesis 1: a potential oncogenic driver

10 Aug 2023

Abstract excerpt

Protein regulator of cytokinesis 1 (PRC1) is involved in cytokinesis. Growing evidence suggests the association of PRC1 with multiple cancers. Here, we unveil that, in 28 cancer types, PRC1 is higher expressed in tumor tissues than in non-malignant tissues. Overexpression of PRC1 indicates unfavorable prognostic value, especially in ACC, LGG, KIRP, LICH, LUAD, MESO, PAAD, SARC and UCEC, while methylation of the...

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PMID: 37563591
DOI: 10.1186/s12943-023-01802-1

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