Article
Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.
Cancer science - 1 Feb 2007
Shimo Arata, Nishidate Toshihiko, Ohta Tomohiko, Fukuda Mamoru, Nakamura Yusuke, Katagiri Toyomasa
Abstract excerpt
To elucidate molecular mechanisms of mammary carcinogenesis and discover novel therapeutic targets for breast cancer, we previously carried out a genome-wide expression profile analysis of 81 breast cancer cases by means of a combination of cDNA microarray and laser microbeam microdissection. Among the upregulated genes, we focused on the functional significance of protein regulator of cytokinesis 1 (PRC1) in the...
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