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Article

Identifying cellular senescence associated genes involved in the progression of end-stage renal disease as new biomarkers.

BMC nephrology - 8 Aug 2023

Xi Yu-Jia, Guo Qiang, Zhang Ran, Duan Guo-Sheng, Zhang Sheng-Xiao

Abstract excerpt

BACKGROUND: Cellular senescence plays an essential role in the development and progression of end-stage renal disease (ESRD). However, the detailed mechanisms phenomenon remains unclear. METHODS: The mRNA expression profiling dataset GSE37171 was taken from the Gene Expression Omnibus (GEO) database. The cell senescence-associated hub genes were selected by applying protein-protein interaction (PPI), followed by...

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PMID: 37553608
DOI: 10.1186/s12882-023-03285-0
PMCID: PMC10408218

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