Article
A critical inter-subunit interaction for the transmission of the allosteric signal in the Agrobacterium tumefaciens ADP-glucose pyrophosphorylase.
Protein science : a publication of the Protein Society - 1 Sept 2023
Patel Hiral P, Martinez-Ramirez Gabriela, Dobrzynski Emily, Iglesias Alberto A, Liu Dali, Ballicora Miguel A
Abstract excerpt
ADP-glucose pyrophosphorylase is a key regulatory enzyme involved in starch and glycogen synthesis in plants and bacteria, respectively. It has been hypothesized that inter-subunit communications are important for the allosteric effect in this enzyme. However, no specific interactions have been identified as part of the regulatory signal. The enzyme from Agrobacterium tumefaciens is a homotetramer allosterically...
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