Article
Unraveling the activation mechanism of the potato tuber ADP-glucose pyrophosphorylase.
PloS one - 1 Jan 2013
Figueroa Carlos M, Kuhn Misty L, Falaschetti Christine A, Solamen Ligin, Olsen Kenneth W, Ballicora Miguel A, Iglesias Alberto A
Abstract excerpt
ADP-glucose pyrophosphorylase regulates the synthesis of glycogen in bacteria and of starch in plants. The enzyme from plants is mainly activated by 3-phosphoglycerate and is a heterotetramer comprising two small and two large subunits. Here, we found that two highly conserved residues are critical for triggering the activation of the potato tuber ADP-glucose pyrophosphorylase, as shown by site-directed...
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