Article
Enhanced heterotetrameric assembly of potato ADP-glucose pyrophosphorylase using reverse genetics.
Plant & cell physiology - 1 Aug 2014
Seferoglu A Bengisu, Koper Kaan, Can F Betul, Cevahir Gul, Kavakli I Halil
Abstract excerpt
ADP-glucose pyrophosphorylase (AGPase) is a key allosteric enzyme in plant starch biosynthesis. Plant AGPase is a heterotetrameric enzyme that consists of large (LS) and small subunits (SS), which are encoded by two different genes. Computational and experimental studies have revealed that the heterotetrameric assembly of AGPase is thermodynamically weak. Modeling studies followed by the mutagenesis of the LS of...
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