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Impact of age and telomere length on circulating T cells and rejection risk after lung transplantation for idiopathic pulmonary fibrosis

5 Aug 2023

Abstract excerpt

BACKGROUND: Most idiopathic pulmonary fibrosis (IPF) lung transplant recipients (IPF-LTRs) have short telomere (ST) length. Inherited mutations in telomere-related genes are associated with the development of T cell immunodeficiency. Despite this, IPF-LTRs with telomere-related rare variants are not protected from acute cellular rejection (ACR). We set out to determine the impact of both age and telomere length...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Telomeres, Telomerase, and Senescence
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37544465
DOI: 10.1016/j.healun.2023.08.001

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