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Changing clinical significance of oocyte maturity grades with advancing female age advances precision medicine in IVF

11 Jul 2023

Abstract excerpt

In current IVF practice, metaphase-2 (M2) oocytes are considered most efficient in producing good quality embryos. Maximizing their number at all ages is standard clinical practice, while immature germinal vesicle (GV) oocytes are mostly automatically discarded. We present preliminary evidence that oocyte maturity grades with advancing age significantly change in their abilities to produce good quality embryos,...

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Identifiers

PMID: 37539038
DOI: 10.1016/j.isci.2023.107308

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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