Article
Use of Tirofiban to Prevent Ischemic Events in Patients with CYP2C19 Loss-of-Function Alleles during Flow Diversion of Intracranial Aneurysm: A Multicenter Cohort Study.
Translational stroke research - 1 Oct 2024
Zhou Yangyang, Kang Huibin, Li Wenqiang, Luo Bin, Wang Chao, Xie Ruhang, Zhu Yongnan, Peng Qichen, Zhang Yisen, Liu Jian, Zhang Ying, Mu Shiqing, Guan Sheng, Feng Wenfeng, Yang Xinjian
Abstract excerpt
To analyze the effect of tirofiban on ischemic events in CYP2C19 loss-of-function (LOF) allele carriers during pipeline embolization device (PED) implantation. Demographic information, imaging data, ischemic complications, CYP2C19 genotyping, and platelet function test results were collected from patients with PED-treated intracranial aneurysms at three centers. Multivariate logistic regression was used to...
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