Article
CYP2C19 genotype-guided antiplatelet therapy to prevent thromboembolic events after stent-assisted coil embolization of unruptured intracranial aneurysms: a retrospective cohort study.
Journal of neurointerventional surgery - 14 May 2026
Yang Mingdong, Zhang Xiaoyu, Xu Junjun, Wang Yuhan, Lin Tao, Xu Huimin, Chen Jie, Dai Yunjian, Yu Lingyan, Wei Zhenli, Zhu Tao, Hu Wei, Hu Yangmin, Xu Ding, Dai Haibin
Abstract excerpt
BACKGROUND: CYP2C19 genotyping has been widely studied to guide antiplatelet therapy in cardiovascular disease; however, its role in neurointerventional procedures, particularly for unruptured intracranial aneurysms (UIA), remains underexplored. This study aimed to evaluate the clinical utility of CYP2C19-guided antiplatelet therapy following stent-assisted coil embolization (SAC) in patients with UIA. METHODS: A...
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