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Article

Does the clopidogrel CYP2C19 genotype assay predict postprocedure stenosis in cerebral aneurysms treated with a flow diverter?

Neurosurgical focus - 1 Oct 2023

Allen Austin J, Gelinne Aaron, Quig Nathan S, Reed Samuel, Shastri Darshan, Ho James P, Yap Edward

Abstract excerpt

OBJECTIVE: Flow diverters have emerged as a popular modality for treating cerebral aneurysms but require dual antiplatelet therapy (DAPT) after placement. Clopidogrel is a common choice but is a prodrug that some patients may not convert into an active metabolite. The CYP2C19 genotype assay is used to predict activation speed; however, limited data exist showcasing whether this genotype accurately predicts...

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Share to Clopidogrel
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP2C19

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Identifiers

PMID: 37778046
DOI: 10.3171/2023.7.FOCUS23373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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