Article
FTO Polymorphisms are Associated with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Susceptibility in the Older Chinese Han Population.
Clinical interventions in aging - 1 Jan 2020
Gu Zhan, Bi Yan, Yuan Fan, Wang Ruirui, Li Dong, Wang Jianying, Hu Xiaojuan, He Guang, Zhang Lei, Liu Bao-Cheng
Abstract excerpt
BACKGROUND: As fat and obesity play a vital role in the pathophysiology of metabolic dysfunction-associated fatty liver disease (MAFLD), this study aims to investigate the association between the fat mass and obesity-associated gene (FTO) and MAFLD. METHODS: Six SNPs (rs6499640, rs1421085, rs8050136, rs3751812, rs9939609 and ) within FTO were genotyped for 741 MAFLD patients (median age, 69.98;...