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The influence of tissue pH and RNA integrity number on gene expression of human postmortem brain

14 Jul 2023

Abstract excerpt

Background: Evaluating and controlling confounders are necessary when investigating molecular pathogenesis using human postmortem brain tissue. Particularly, tissue pH and RNA integrity number (RIN) are valuable indicators for controlling confounders. However, the influences of these indicators on the expression of each gene in postmortem brain have not been fully investigated. Therefore, we aimed to assess these...

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PMID: 37520228
DOI: 10.3389/fpsyt.2023.1156524

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