Article
Value of GCET1, HGAL (GCET2), and LMO2 in the Determination of Germinal Center Phenotype in Diffuse Large B-cell Lymphoma
Turkish journal of haematology : official journal of Turkish Society of Haematology - 31 Aug 2023
Berker Neslihan, Yeğen Gülçin, Özlük Yasemin, Doğan Öner
Abstract excerpt
Objective: Diffuse large B-cell lymphoma (DLBCL) is a biologically heterogeneous disease that is classified into germinal center B-cell (GCB) and non-GCB subtypes, which are prognostically different. The Hans algorithm is the most widely used tool based on CD10, BCL6, and MUM1 expression, but some cases with the non-GCB phenotype are still known to be misclassified. In this study, we investigate the extent to...
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