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Article

Intermittent Hypoxia Mediates Cancer Development and Progression Through HIF-1 and miRNA Regulation

9 Jul 2023

Abstract excerpt

INTRODUCTION: There is still a debate for the link between obstructive sleep apnoea (OSA) and cancer. The mechanisms underlying this causality are poorly understood. Several miRNAs are involved in cancer development and progression with expression being influenced by hypoxia. The aims of this work were (i) to compare miRNAs expression in controls versus patients affected by OSA without or with cancer (ONCO-OSA)...

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PMID: 37517933
DOI: 10.1016/j.arbres.2023.07.001

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