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The Complex Role of Chaperone-Mediated Autophagy in Cancer Diseases

20 Jul 2023

Abstract excerpt

Chaperone-mediated autophagy (CMA) is a process that rapidly degrades proteins labeled with KFERQ-like motifs within cells via lysosomes to terminate their cellular functioning. Meanwhile, CMA plays an essential role in various biological processes correlated with cell proliferation and apoptosis. Previous studies have shown that CMA was initially found to be procancer in cancer cells, while some theories suggest...

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PMID: 37509689
DOI: 10.3390/biomedicines11072050

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