Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancer

11 Mar 2021

Abstract excerpt

Screening for early-stage disease is vital for reducing colorectal cancer (CRC)-related mortality. Methylation of circulating tumor DNA has been previously used for various types of cancer screening. A novel cell-free DNA (cfDNA) methylation-based model which can improve the early detection of CRC is warranted. For our study, we collected 313 tissue and 577 plasma samples from patients with CRC, advanced adenoma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33694305
DOI: 10.1002/1878-0261.12942

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel cell‐free DNA methylation‐based model improves the early detection of colorectal cancerPMID 33694305Read ↗

Cell-free DNA methylation profiles enable early detection of colorectal and gastric cancerSemantic proximity Read ↗

Genome-wide discovery of circulating cell-free DNA methylation biomarkers for colorectal cancer detectionSemantic proximity Read ↗

Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case–control studySemantic proximity Read ↗

Efficacy of cell-free DNA methylation-based blood test for colorectal cancer screening in high-risk population: a prospective cohort studySemantic proximity Read ↗

Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and SequencingSemantic proximity Read ↗

Discovery and Validation of Methylation Signatures in Circulating Cell-Free DNA for the Detection of Colorectal CancerSemantic proximity Read ↗

Circulating tumor DNA methylation profiles enable early diagnosis, prognosis prediction, and screening for colorectal cancerSemantic proximity Read ↗

Early detection and prognosis prediction for colorectal cancer by circulating tumour DNA methylation haplotypes: a multicentre cohort studySemantic proximity Read ↗

Abnormal DNA methylation as a cell-free circulating DNA biomarker for colorectal cancer detection: A review of literatureSemantic proximity Read ↗

DNA methylation biomarkers in colorectal cancer: Clinical applications for precision medicineSemantic proximity Read ↗

Evaluation of a plasma cell-free DNA methylation test for colorectal cancer diagnosis: a multicenter clinical studySemantic proximity Read ↗

A 5-Hydroxymethylcytosine-Based Noninvasive Model for Early Detection of Colorectal Carcinomas and Advanced Adenomas: The METHOD-2 StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.