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GPR81-mediated reprogramming of glucose metabolism contributes to the immune landscape in breast cancer

27 Jul 2023

Abstract excerpt

Abstract Background Local tumor microenvironment (TME) plays a crucial role in immunotherapy for breast cancer (BC). Whereas, the molecular mechanism responsible for the crosstalk between BC cells and surrounding immune cells remains unclear. The present study aimed to determine the interplay between GPR81-mediated glucometabolic reprogramming of BC and the immune landscape in TME. Materials and Methods...

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PMID: 37500811
DOI: 10.1007/s12672-023-00709-z

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