Article
MiR-552-3p Regulates Multiple Fibrotic and Inflammatory genes Concurrently in Hepatic Stellate Cells Improving NASH-associated Phenotypes.
International journal of biological sciences - 1 Jan 2023
Ma Ningning, Hou Aijun, Pan Xiangyu, Sun Fuguang, Xu Xiaoding, Yu Chuwei, Lai Rongtao, Huang Ruimin, Gong Likun, Xie Qing, Chen Jing, Ren Jin
Abstract excerpt
Non-alcoholic steatohepatitis (NASH) is a chronic liver disease characterized by hepatic steatosis, inflammation, and progressive fibrosis. Our previous study demonstrated that microRNA-552-3p (miR-552-3p) was down-regulated in the livers of patients with NASH and alleviated hepatic glycolipid metabolic disorders. However, whether miR-552-3p affects NASH progression remains unclear. In this current study, we...
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