Article
Incomplete dominance of deleterious alleles contributes substantially to trait variation and heterosis in maize.
PLoS genetics - 1 Sept 2017
Yang Jinliang, Mezmouk Sofiane, Baumgarten Andy, Buckler Edward S, Guill Katherine E, McMullen Michael D, Mumm Rita H, Ross-Ibarra Jeffrey
Abstract excerpt
Deleterious alleles have long been proposed to play an important role in patterning phenotypic variation and are central to commonly held ideas explaining the hybrid vigor observed in the offspring of a cross between two inbred parents. We test these ideas using evolutionary measures of sequence conservation to ask whether incorporating information about putatively deleterious alleles can inform genomic selection...
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