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Genetic basis of ß-thalassemia in families of pashtun ethnicity in Dera Ismail Khan district of Khyber Pakhtun-Khwa province, Pakistan.

Expert review of hematology - 1 Jan 2000

Ayaz Muhammad, Muzammal Muhammad, Siraj Sami, Fatima Sumaya, Fatima Sana, Khan Jabbar, Khan Muzammil Ahmad, Shah Muhammad Ishaq, Rehman Zia Ur, Wei Lin

Abstract excerpt

OBJECTIVES: The objective of current genetic research was to verify the genetic basis of ß-thalassemia and its pattern of inheritance in families of Pashtun ethnicity in District Dera Ismail Khan, Pakistan. METHODOLOGY: Blood samples from clinically diagnosed five unrelated ß-thalassemia families were collected and target Sanger Sequencing of HBB gene was done. Moreover, in silico analysis including protein...

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PMID: 37491848
DOI: 10.1080/17474086.2023.2241639

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