Genetics of Pancreatic Neuroendocrine Tumors.

Abstract excerpt

Pancreatic neuroendocrine tumors (pNETs) represent a relatively rare disease; however, the incidence has been increasing during the last 2 decades. Next generation sequencing has greatly increased our understanding of driver mutations in pNETs. Sporadic pNETs have consistently presented with mutations in MEN1, DAXX/ATRX, and genes related to the mammalian target of rapamycin pathway. Inherited pNETs have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Mutation
• Share to Neuroendocrine Tumors
• Share to Pancreatic Neoplasms