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Article

Immunometabolism mRNA expression phenotypes and reprogramming of CD14 in T2DM with or without CVD.

International immunopharmacology - 1 Sept 2023

Bendaya Imen, Ben Jemaa Awatef, Sahraoui Ghada, Kharrat Maher, Sdiri Wissem, Oueslati Ridha

Abstract excerpt

BACKGROUND/AIM: Type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVD) have a significant impact on the expression of genes in peripheral blood mononuclear cells (PBMCs). The primary objective of this study was to investigate the role of two signaling pathways, STAT1/6, and two important modulators of immunometabolism, leptin and PPARs, in the development of T2DM with and without CVD. Furthermore, the...

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Cardiovascular Diseases
Diabetes Mellitus, Type 2
Leptin
Leukocytes, Mononuclear
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37487262
DOI: 10.1016/j.intimp.2023.110665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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