Article
Inability of chlorophenols to induce 6-thioguanine-resistant mutants in V79 Chinese hamster cells.
Mutation research - 1 Jan 2000
Jansson K, Jansson V
Abstract excerpt
The induction of mutation at the hypoxanthine-guanine phosphoribosyl transferase locus and cytotoxicities of 6 different chlorophenols (2,4- and 2,6-dichlorophenol, 2,4,5- and 2,4,6-trichlorophenol, 2,3,4,6-tetrachlorophenol and pentachlorophenol) were examined in V79 Chinese hamster cells without exogenous metabolic activation. The chlorophenols were cytotoxic to V79 cells, but failed to produce significant...
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