Article
2,4-Dichlorophenoxyacetic acid causes chromatin and chromosome abnormalities in plant cells and mutation in cultured mammalian cells.
Mutation research - 1 Jun 1991
Pavlica M, Papes D, Nagy B
Abstract excerpt
The cytotoxic and mutagenic effects of the synthetic auxin 2,4-dichlorophenoxyacetic acid (2,4-D) on shallot root tip cells and on V79 Chinese hamster fibroblast cells were examined and compared. In shallot root tips 2,4-D caused changes in mitotic activity, as well as changes in chromosome and chromatin structure, and also changes during the cell cycle. 2,4-D also showed mutagenic and cytotoxic effects on V79...
Topics
- 2,4-Dichlorophenoxyacetic Acid
- Allium
- Cell Line
- Cell Survival
- Cells, Cultured
- Chromatin
- Chromosome Aberrations
- Fibroblasts
- Micronuclei, Chromosome-Defective
- Mutagenicity Tests
- Mutation