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Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank

20 Jul 2023

Abstract excerpt

BACKGROUND: Identifying prediagnostic neurodegenerative disease is a critical issue in neurodegenerative disease research, and Alzheimer's disease (AD) in particular, to identify populations suitable for preventive and early disease-modifying trials. Evidence from genetic and other studies suggests the neurodegeneration of Alzheimer's disease measured by brain atrophy starts many years before diagnosis, but it is...

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PMID: 37474615
DOI: 10.1038/s43856-023-00313-w

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