Article
Serum concentrations of IL-16 and its genetic polymorphism rs4778889 affect the susceptibility and severity of endometriosis in Nigerian women.
BMC women's health - 11 May 2023
Babah Ochuwa Adiketu, Ojewunmi Oyesola Oyewole, Onwuamah Chika Kingsley, Udenze Ifeoma Christiana, Osuntoki Akinniyi Adediran, Afolabi Bosede Bukola
Abstract excerpt
BACKGROUND: Endometriosis is the presence of active ectopic endometrial glands and stroma at other sites outside the uterine cavity. It is a common cause of chronic pelvic pain which is sometimes debilitating, and inflammation is one of the known triggers of endometriosis. Interleukins 6 and 16 (IL-6 and IL-16) are proinflammatory cytokines which play essential roles in inflammatory diseases. We therefore...
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